AOD-9604

AOD-9604 — Growth Hormone Fragment 176-191

AOD-9604 is a modified synthetic peptide fragment corresponding to the C-terminal region (amino acids 176-191) of human growth hormone (hGH). This specific fragment retains the lipolytic activity of full-length GH while lacking its growth-promoting and diabetogenic effects, making it a uniquely targeted research tool for fat metabolism studies.

Mechanism of Action

AOD-9604 stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat accumulation) through a mechanism independent of the growth hormone receptor. Research indicates it activates the beta-3 adrenergic receptor pathway and enhances calcium-dependent fat oxidation. Importantly, AOD-9604 does not affect IGF-1 levels, blood glucose, or insulin sensitivity — allowing researchers to isolate fat metabolism pathways without confounding growth or glycemic variables.

Research Applications

• Lipolysis and fat metabolism pathway studies
• Adipocyte biology and lipogenesis inhibition
• Beta-3 adrenergic receptor signaling research
• Cartilage repair and osteoarthritis studies
• Comparative studies with full-length GH fragments

Product Specifications

• Quantity: 5mg per vial
• Purity: ≥98% (HPLC verified)
• Form: Lyophilized powder
• Storage: Refrigerate after reconstitution
• Testing: USA lab tested, COA available

For research purposes only. Not for human use or consumption.